The X-inactivation trans-activator Rnf12 is negatively regulated by pluripotency factors in embryonic stem cells

X-inactivation, the molecular mechanism enabling dosage compensation in mammals, is tightly controlled during mouse early embryogenesis. In the morula, X-inactivation is imprinted with exclusive silencing of the paternally inherited X-chromosome. In contrast, in the post-implantation epiblast, X-ina...

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Detalles Bibliográficos
Autores principales: Navarro, Pablo, Moffat, Michael, Mullin, Nicholas P., Chambers, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132432/
https://www.ncbi.nlm.nih.gov/pubmed/21544581
http://dx.doi.org/10.1007/s00439-011-0998-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132432/
https://www.ncbi.nlm.nih.gov/pubmed/21544581
http://dx.doi.org/10.1007/s00439-011-0998-5

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