Volumetric Differences in Mapped Hippocampal Regions Correlate with Increase of High Alpha Rhythm in Alzheimer's Disease

Objective. The increase of high alpha relative to low alpha power has been recently demonstrated as a reliable EEG marker of hippocampal atrophy conversion of patients with mild cognitive impairment (MCI) in Alzheimer's disease (AD). In the present study we test the reliability of this EEG inde...

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Autores principales: Moretti, D. V., Prestia, A., Fracassi, C., Geroldi, C., Binetti, G., Rossini, P. M., Zanetti, O., Frisoni, G. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132513/
https://www.ncbi.nlm.nih.gov/pubmed/21760984
http://dx.doi.org/10.4061/2011/208218
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author Moretti, D. V.
Prestia, A.
Fracassi, C.
Geroldi, C.
Binetti, G.
Rossini, P. M.
Zanetti, O.
Frisoni, G. B.
author_facet Moretti, D. V.
Prestia, A.
Fracassi, C.
Geroldi, C.
Binetti, G.
Rossini, P. M.
Zanetti, O.
Frisoni, G. B.
author_sort Moretti, D. V.
collection PubMed
description Objective. The increase of high alpha relative to low alpha power has been recently demonstrated as a reliable EEG marker of hippocampal atrophy conversion of patients with mild cognitive impairment (MCI) in Alzheimer's disease (AD). In the present study we test the reliability of this EEG index in subjects with AD. Methods. Correlation between EEG markers and volumetric differences in mapped hippocampal regions was estimated in AD patients. Results. Results show that the increase of alpha3/alpha2 power ratio is correlated with atrophy of mapped hippocampal regions in Alzheimer's disease. Conclusions. The findings confirm the possible diagnostic role of EEG markers.
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spelling pubmed-31325132011-07-14 Volumetric Differences in Mapped Hippocampal Regions Correlate with Increase of High Alpha Rhythm in Alzheimer's Disease Moretti, D. V. Prestia, A. Fracassi, C. Geroldi, C. Binetti, G. Rossini, P. M. Zanetti, O. Frisoni, G. B. Int J Alzheimers Dis Research Article Objective. The increase of high alpha relative to low alpha power has been recently demonstrated as a reliable EEG marker of hippocampal atrophy conversion of patients with mild cognitive impairment (MCI) in Alzheimer's disease (AD). In the present study we test the reliability of this EEG index in subjects with AD. Methods. Correlation between EEG markers and volumetric differences in mapped hippocampal regions was estimated in AD patients. Results. Results show that the increase of alpha3/alpha2 power ratio is correlated with atrophy of mapped hippocampal regions in Alzheimer's disease. Conclusions. The findings confirm the possible diagnostic role of EEG markers. SAGE-Hindawi Access to Research 2011-06-14 /pmc/articles/PMC3132513/ /pubmed/21760984 http://dx.doi.org/10.4061/2011/208218 Text en Copyright © 2011 D. V. Moretti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Moretti, D. V.
Prestia, A.
Fracassi, C.
Geroldi, C.
Binetti, G.
Rossini, P. M.
Zanetti, O.
Frisoni, G. B.
Volumetric Differences in Mapped Hippocampal Regions Correlate with Increase of High Alpha Rhythm in Alzheimer's Disease
title Volumetric Differences in Mapped Hippocampal Regions Correlate with Increase of High Alpha Rhythm in Alzheimer's Disease
title_full Volumetric Differences in Mapped Hippocampal Regions Correlate with Increase of High Alpha Rhythm in Alzheimer's Disease
title_fullStr Volumetric Differences in Mapped Hippocampal Regions Correlate with Increase of High Alpha Rhythm in Alzheimer's Disease
title_full_unstemmed Volumetric Differences in Mapped Hippocampal Regions Correlate with Increase of High Alpha Rhythm in Alzheimer's Disease
title_short Volumetric Differences in Mapped Hippocampal Regions Correlate with Increase of High Alpha Rhythm in Alzheimer's Disease
title_sort volumetric differences in mapped hippocampal regions correlate with increase of high alpha rhythm in alzheimer's disease
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132513/
https://www.ncbi.nlm.nih.gov/pubmed/21760984
http://dx.doi.org/10.4061/2011/208218
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