Cargando…

Bridging Molecular Genetics and Biomarkers in Lewy Body and Related Disorders

Recent advances have been made in defining the genetic and molecular basis of dementia with Lewy bodies (DLBs) and related neurodegenerative disorders such as Parkinson's disease (PD) and Parkinson's disease dementia (PDD) which comprise the spectrum of “Lewy body disorders” (LBDs). The ge...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ho, Gilbert J., Liang, Willie, Waragai, Masaaki, Sekiyama, Kazunari, Masliah, Eliezer, Hashimoto, Makoto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE-Hindawi Access to Research 2011
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132544/ https://www.ncbi.nlm.nih.gov/pubmed/21760990 http://dx.doi.org/10.4061/2011/842475

Ejemplares similares

Importance of adiponectin activity in the pathogenesis of Alzheimer's disease
por: Waragai, Masaaki, et al.
Publicado: (2017)

α-Synuclein and DJ-1 as Potential Biological Fluid Biomarkers for Parkinson’s Disease
por: Waragai, Masaaki, et al.
Publicado: (2010)

Distinct mechanisms of axonal globule formation in mice expressing human wild type α-synuclein or dementia with Lewy bodies-linked P123H ß-synuclein
por: Sekigawa, Akio, et al.
Publicado: (2012)

Reconsideration of Alzheimer’s Disease Therapy from a Viewpoint of Amyloidogenic Evolvability
por: Ho, Gilbert, et al.
Publicado: (2022)

Neuroinflammation in Parkinson's Disease and Related Disorders: A Lesson from Genetically Manipulated Mouse Models of α-Synucleinopathies
por: Sekiyama, Kazunari, et al.
Publicado: (2012)

Evolvability of Amyloidogenic Proteins in Human Brain
por: Hashimoto, Makoto, et al.
Publicado: (2018)

Evolvability and Neurodegenerative Disease: Antagonistic Pleiotropy Phenomena Derived from Amyloid Aggregates
por: Hashimoto, Makoto, et al.
Publicado: (2018)

Possible Role of the Polyglutamine Elongation in Evolution of Amyloid-Related Evolvability
por: Hashimoto, Makoto, et al.
Publicado: (2018)

Transgenerational Interaction of Alzheimer’s Disease with Schizophrenia through Amyloid Evolvability
por: Takamatsu, Yoshiki, et al.
Publicado: (2019)

Adiponectin Paradox as a Therapeutic Target in Alzheimer’s Disease
por: Waragai, Masaaki, et al.
Publicado: (2020)

Understanding Creutzfeldt-Jackob disease from a viewpoint of amyloidogenic evolvability
por: Hashimoto, Makoto, et al.
Publicado: (2020)

Possible Role of Amyloid Cross-Seeding in Evolvability and Neurodegenerative Disease
por: Hashimoto, Makoto, et al.
Publicado: (2019)

Adiponectin Paradox in Alzheimer's Disease; Relevance to Amyloidogenic Evolvability?
por: Waragai, Masaaki, et al.
Publicado: (2020)

Connecting Alzheimer’s Disease With Diabetes Mellitus Through Amyloidogenic Evolvability
por: Ho, Gilbert, et al.
Publicado: (2020)

Possible Role of Activin in the Adiponectin Paradox-Induced Progress of Alzheimer’s Disease
por: Hashimoto, Makoto, et al.
Publicado: (2021)

Combined immunotherapy with “anti-insulin resistance” therapy as a novel therapeutic strategy against neurodegenerative diseases
por: Takamatsu, Yoshiki, et al.
Publicado: (2017)

Disease modifying effect of adiponectin in model of α-synucleinopathies
por: Sekiyama, Kazunari, et al.
Publicado: (2014)

Motor and Nonmotor Symptoms of Parkinson's Disease: Antagonistic Pleiotropy Phenomena Derived from α-Synuclein Evolvability?
por: Takamatsu, Yoshiki, et al.
Publicado: (2018)

A β-synuclein mutation linked to dementia produces neurodegeneration when expressed in mouse brain
por: Fujita, Masayo, et al.
Publicado: (2010)

Diversity of Mitochondrial Pathology in a Mouse Model of Axonal Degeneration in Synucleinopathies
por: Sekigawa, Akio, et al.
Publicado: (2013)

Protection against neurodegenerative disease on Earth and in space
por: Takamatsu, Yoshiki, et al.
Publicado: (2016)

Selective Molecular Alterations in the Autophagy Pathway in Patients with Lewy Body Disease and in Models of α-Synucleinopathy
por: Crews, Leslie, et al.
Publicado: (2010)

Differential involvement of amyloidogenic evolvability in oligodendropathies; Multiple Sclerosis and Multiple System Atrophy
por: Wei, Jianshe, et al.
Publicado: (2023)

Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology
por: Ngolab, Jennifer, et al.
Publicado: (2017)

Correction to: Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology
por: Ngolab, Jennifer, et al.
Publicado: (2020)

Therapeutic Potential of α-Synuclein Evolvability for Autosomal Recessive Parkinson's Disease
por: Wei, Jianshe, et al.
Publicado: (2021)

Biomarkers in Alzheimer's Disease and Lewy Body Disorders with Dementia
por: Leyhe, Thomas, et al.
Publicado: (2013)

α‐synuclein conformational antibodies fused to penetratin are effective in models of Lewy body disease
por: Spencer, Brian, et al.
Publicado: (2016)

Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models
por: Iba, Michiyo, et al.
Publicado: (2020)

Diabetes, inflammation, and the adiponectin paradox: Therapeutic targets in SARS-CoV-2
por: Ho, Gilbert, et al.
Publicado: (2021)

Gastrointestinal disorders in Parkinson’s disease and other Lewy body diseases
por: Hirayama, Masaaki, et al.
Publicado: (2023)

Effects of Novel Calpain Inhibitors in Transgenic Animal Model of Parkinson’s disease/dementia with Lewy bodies
por: Hassen, Getaw Worku, et al.
Publicado: (2018)

Neurophysiological biomarkers for Lewy body dementias
por: Cromarty, Ruth A., et al.
Publicado: (2016)

Clinical biomarkers for Lewy body diseases
por: Abdelmoaty, Mai M., et al.
Publicado: (2023)

Therapeutic Potential of αS Evolvability for Neuropathic Gaucher Disease
por: Wei, Jianshe, et al.
Publicado: (2021)

Possible Role of Amyloidogenic Evolvability in Dementia with Lewy Bodies: Insights from Transgenic Mice Expressing P123H β-Synuclein
por: Fujita, Masayo, et al.
Publicado: (2020)

Role of Alterations in Protein Kinase p38γ in the Pathogenesis of the Synaptic Pathology in Dementia With Lewy Bodies and α-Synuclein Transgenic Models
por: Iba, Michiyo, et al.
Publicado: (2020)

Role of α- and β-Synucleins in the Axonal Pathology of Parkinson’s Disease and Related Synucleinopathies
por: Sekigawa, Akio, et al.
Publicado: (2015)

Advancing the Genetics of Lewy Body Disorders with Disease‐Modifying Treatments in Mind
por: Levy, Gilberto, et al.
Publicado: (2022)

Neural Stem Cells Rescue Cognitive and Motor Dysfunction in a Transgenic Model of Dementia with Lewy Bodies through a BDNF-Dependent Mechanism
por: Goldberg, Natalie R.S., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_2mmhk99luqqu23jqm4clqab896