Synthesis and In Vitro Evaluation of Novel Nortropane Derivatives as Potential Radiotracers for Muscarinic M(2) Receptors

Disturbances of the cerebral cholinergic neurotransmitter system are present in neurodegenerative disorders. SPECT or PET imaging, using radiotracers that selectively target muscarinic receptor subtypes, may be of value for in vivo evaluation of such conditions. 6β-acetoxynortropane, a potent muscar...

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Detalles Bibliográficos
Autores principales: Knol, Remco J. J., van den Bos, Jan C., Janssen, Anton G. M., de Bruin, Kora, van Eck-Smit, Berthe L. F., Booij, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132655/
https://www.ncbi.nlm.nih.gov/pubmed/21755053
http://dx.doi.org/10.1155/2011/709416

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