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Liposome-based DNA carriers may induce cellular stress response and change gene expression pattern in transfected cells

BACKGROUND: During functional studies on the rat stress-inducible Hspa1b (hsp70.1) gene we noticed that some liposome-based DNA carriers, which are used for transfection, induce its promoter activity. This observation concerned commercial liposome formulations (LA), Lipofectin and Lipofectamine 2000...

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Detalles Bibliográficos
Autores principales:	Fiszer-Kierzkowska, Anna, Vydra, Natalia, Wysocka-Wycisk, Aleksandra, Kronekova, Zuzana, Jarząb, Michał, Lisowska, Katarzyna Marta, Krawczyk, Zdzisław
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132718/ https://www.ncbi.nlm.nih.gov/pubmed/21663599 http://dx.doi.org/10.1186/1471-2199-12-27

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