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Remodeling Lipid Metabolism and Improving Insulin Responsiveness in Human Primary Myotubes
OBJECTIVE: Disturbances in lipid metabolism are strongly associated with insulin resistance and type 2 diabetes (T2D). We hypothesized that activation of cAMP/PKA and calcium signaling pathways in cultured human myotubes would provide further insight into regulation of lipid storage, lipolysis, lipi...
Autores principales: | Sparks, Lauren M., Moro, Cedric, Ukropcova, Barbara, Bajpeyi, Sudip, Civitarese, Anthony E., Hulver, Matthew W., Thoresen, G. Hege, Rustan, Arild C., Smith, Steven R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132732/ https://www.ncbi.nlm.nih.gov/pubmed/21760887 http://dx.doi.org/10.1371/journal.pone.0021068 |
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