Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis

Chromosomal instability is a major pathway of sporadic colon carcinogenesis. Chromosome arm 1p appears to be one of the “hot spots” in the non-neoplastic mucosa that, when deleted, is associated with the initiation of carcinogenesis. Chromosome arm 1p contains genes associated with DNA repair, spind...

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Detalles Bibliográficos
Autores principales: Payne, Claire M, Crowley-Skillicorn, Cheray, Bernstein, Carol, Holubec, Hana, Bernstein, Harris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132853/
https://www.ncbi.nlm.nih.gov/pubmed/21753893
http://dx.doi.org/10.2147/CEG.S17114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132853/
https://www.ncbi.nlm.nih.gov/pubmed/21753893
http://dx.doi.org/10.2147/CEG.S17114

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