Parametric Images in Assessing Bone Grafts Using Dynamic (18)F-Fluoride PET

The early identification of graft failure would improve patient management. (18)F-fluoride is a suitable tracer for quantifying bone metabolism. Performance of parametric images constructed by Patlak graphical analysis (PGA) with various time periods was evaluated in the analysis of dynamic (18)F-fl...

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Detalles Bibliográficos
Autores principales: Wen, Lingfeng, Eberl, Stefan, Feng, (David) Dagan, Stalley, Paul, Huang, Gang, Fulham, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132866/
https://www.ncbi.nlm.nih.gov/pubmed/21755052
http://dx.doi.org/10.1155/2011/189830
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author Wen, Lingfeng
Eberl, Stefan
Feng, (David) Dagan
Stalley, Paul
Huang, Gang
Fulham, Michael J.
author_facet Wen, Lingfeng
Eberl, Stefan
Feng, (David) Dagan
Stalley, Paul
Huang, Gang
Fulham, Michael J.
author_sort Wen, Lingfeng
collection PubMed
description The early identification of graft failure would improve patient management. (18)F-fluoride is a suitable tracer for quantifying bone metabolism. Performance of parametric images constructed by Patlak graphical analysis (PGA) with various time periods was evaluated in the analysis of dynamic (18)F-fluoride PET studies of eight patients with fibula bone grafts after limb salvage surgery. The PGA parametric image approach tended to underestimate influx rate. The linear portion of PGA analysis was found to be from 10 to 50 min. It shows promise in providing a quantitative assessment of the viability of bone grafts.
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spelling pubmed-31328662011-07-13 Parametric Images in Assessing Bone Grafts Using Dynamic (18)F-Fluoride PET Wen, Lingfeng Eberl, Stefan Feng, (David) Dagan Stalley, Paul Huang, Gang Fulham, Michael J. Int J Mol Imaging Research Article The early identification of graft failure would improve patient management. (18)F-fluoride is a suitable tracer for quantifying bone metabolism. Performance of parametric images constructed by Patlak graphical analysis (PGA) with various time periods was evaluated in the analysis of dynamic (18)F-fluoride PET studies of eight patients with fibula bone grafts after limb salvage surgery. The PGA parametric image approach tended to underestimate influx rate. The linear portion of PGA analysis was found to be from 10 to 50 min. It shows promise in providing a quantitative assessment of the viability of bone grafts. Hindawi Publishing Corporation 2011 2011-05-22 /pmc/articles/PMC3132866/ /pubmed/21755052 http://dx.doi.org/10.1155/2011/189830 Text en Copyright © 2011 Lingfeng Wen et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Wen, Lingfeng
Eberl, Stefan
Feng, (David) Dagan
Stalley, Paul
Huang, Gang
Fulham, Michael J.
Parametric Images in Assessing Bone Grafts Using Dynamic (18)F-Fluoride PET
title Parametric Images in Assessing Bone Grafts Using Dynamic (18)F-Fluoride PET
title_full Parametric Images in Assessing Bone Grafts Using Dynamic (18)F-Fluoride PET
title_fullStr Parametric Images in Assessing Bone Grafts Using Dynamic (18)F-Fluoride PET
title_full_unstemmed Parametric Images in Assessing Bone Grafts Using Dynamic (18)F-Fluoride PET
title_short Parametric Images in Assessing Bone Grafts Using Dynamic (18)F-Fluoride PET
title_sort parametric images in assessing bone grafts using dynamic (18)f-fluoride pet
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132866/
https://www.ncbi.nlm.nih.gov/pubmed/21755052
http://dx.doi.org/10.1155/2011/189830
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