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Activity of Cathelicidin Peptides against Simkania negevensis
The in vitro activity of six cathelicidin peptides against the reference strain Z of Simkania negevensis was investigated. Five peptides—PG-1, Bac7, SMAP-29, BMAP-27, and BMAP-28—proved to be active at very low concentrations (1 to 0.1 μg/mL), while LL-37 cathelicidin was ineffective even at a conce...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133470/ https://www.ncbi.nlm.nih.gov/pubmed/21760820 http://dx.doi.org/10.1155/2011/708710 |
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author | Donati, Manuela Di Francesco, Antonietta Di Paolo, Maria Fiani, Natascia Benincasa, Monica Gennaro, Renato Nardini, Paola Foschi, Claudio Cevenini, Roberto |
author_facet | Donati, Manuela Di Francesco, Antonietta Di Paolo, Maria Fiani, Natascia Benincasa, Monica Gennaro, Renato Nardini, Paola Foschi, Claudio Cevenini, Roberto |
author_sort | Donati, Manuela |
collection | PubMed |
description | The in vitro activity of six cathelicidin peptides against the reference strain Z of Simkania negevensis was investigated. Five peptides—PG-1, Bac7, SMAP-29, BMAP-27, and BMAP-28—proved to be active at very low concentrations (1 to 0.1 μg/mL), while LL-37 cathelicidin was ineffective even at a concentration of 100 μg/mL. In comparison to chlamydiae, S. negevensis proved to be more susceptible to the antimicrobial peptides tested. |
format | Online Article Text |
id | pubmed-3133470 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-31334702011-07-14 Activity of Cathelicidin Peptides against Simkania negevensis Donati, Manuela Di Francesco, Antonietta Di Paolo, Maria Fiani, Natascia Benincasa, Monica Gennaro, Renato Nardini, Paola Foschi, Claudio Cevenini, Roberto Int J Pept Research Article The in vitro activity of six cathelicidin peptides against the reference strain Z of Simkania negevensis was investigated. Five peptides—PG-1, Bac7, SMAP-29, BMAP-27, and BMAP-28—proved to be active at very low concentrations (1 to 0.1 μg/mL), while LL-37 cathelicidin was ineffective even at a concentration of 100 μg/mL. In comparison to chlamydiae, S. negevensis proved to be more susceptible to the antimicrobial peptides tested. Hindawi Publishing Corporation 2011 2011-04-05 /pmc/articles/PMC3133470/ /pubmed/21760820 http://dx.doi.org/10.1155/2011/708710 Text en Copyright © 2011 Manuela Donati et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Donati, Manuela Di Francesco, Antonietta Di Paolo, Maria Fiani, Natascia Benincasa, Monica Gennaro, Renato Nardini, Paola Foschi, Claudio Cevenini, Roberto Activity of Cathelicidin Peptides against Simkania negevensis |
title | Activity of Cathelicidin Peptides against Simkania negevensis
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title_full | Activity of Cathelicidin Peptides against Simkania negevensis
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title_fullStr | Activity of Cathelicidin Peptides against Simkania negevensis
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title_full_unstemmed | Activity of Cathelicidin Peptides against Simkania negevensis
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title_short | Activity of Cathelicidin Peptides against Simkania negevensis
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title_sort | activity of cathelicidin peptides against simkania negevensis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133470/ https://www.ncbi.nlm.nih.gov/pubmed/21760820 http://dx.doi.org/10.1155/2011/708710 |
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