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Activity of Cathelicidin Peptides against Simkania negevensis

The in vitro activity of six cathelicidin peptides against the reference strain Z of Simkania negevensis was investigated. Five peptides—PG-1, Bac7, SMAP-29, BMAP-27, and BMAP-28—proved to be active at very low concentrations (1 to 0.1 μg/mL), while LL-37 cathelicidin was ineffective even at a conce...

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Autores principales: Donati, Manuela, Di Francesco, Antonietta, Di Paolo, Maria, Fiani, Natascia, Benincasa, Monica, Gennaro, Renato, Nardini, Paola, Foschi, Claudio, Cevenini, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133470/
https://www.ncbi.nlm.nih.gov/pubmed/21760820
http://dx.doi.org/10.1155/2011/708710
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author Donati, Manuela
Di Francesco, Antonietta
Di Paolo, Maria
Fiani, Natascia
Benincasa, Monica
Gennaro, Renato
Nardini, Paola
Foschi, Claudio
Cevenini, Roberto
author_facet Donati, Manuela
Di Francesco, Antonietta
Di Paolo, Maria
Fiani, Natascia
Benincasa, Monica
Gennaro, Renato
Nardini, Paola
Foschi, Claudio
Cevenini, Roberto
author_sort Donati, Manuela
collection PubMed
description The in vitro activity of six cathelicidin peptides against the reference strain Z of Simkania negevensis was investigated. Five peptides—PG-1, Bac7, SMAP-29, BMAP-27, and BMAP-28—proved to be active at very low concentrations (1 to 0.1 μg/mL), while LL-37 cathelicidin was ineffective even at a concentration of 100 μg/mL. In comparison to chlamydiae, S. negevensis proved to be more susceptible to the antimicrobial peptides tested.
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spelling pubmed-31334702011-07-14 Activity of Cathelicidin Peptides against Simkania negevensis Donati, Manuela Di Francesco, Antonietta Di Paolo, Maria Fiani, Natascia Benincasa, Monica Gennaro, Renato Nardini, Paola Foschi, Claudio Cevenini, Roberto Int J Pept Research Article The in vitro activity of six cathelicidin peptides against the reference strain Z of Simkania negevensis was investigated. Five peptides—PG-1, Bac7, SMAP-29, BMAP-27, and BMAP-28—proved to be active at very low concentrations (1 to 0.1 μg/mL), while LL-37 cathelicidin was ineffective even at a concentration of 100 μg/mL. In comparison to chlamydiae, S. negevensis proved to be more susceptible to the antimicrobial peptides tested. Hindawi Publishing Corporation 2011 2011-04-05 /pmc/articles/PMC3133470/ /pubmed/21760820 http://dx.doi.org/10.1155/2011/708710 Text en Copyright © 2011 Manuela Donati et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Donati, Manuela
Di Francesco, Antonietta
Di Paolo, Maria
Fiani, Natascia
Benincasa, Monica
Gennaro, Renato
Nardini, Paola
Foschi, Claudio
Cevenini, Roberto
Activity of Cathelicidin Peptides against Simkania negevensis
title Activity of Cathelicidin Peptides against Simkania negevensis
title_full Activity of Cathelicidin Peptides against Simkania negevensis
title_fullStr Activity of Cathelicidin Peptides against Simkania negevensis
title_full_unstemmed Activity of Cathelicidin Peptides against Simkania negevensis
title_short Activity of Cathelicidin Peptides against Simkania negevensis
title_sort activity of cathelicidin peptides against simkania negevensis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133470/
https://www.ncbi.nlm.nih.gov/pubmed/21760820
http://dx.doi.org/10.1155/2011/708710
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