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Pediatric Intensive Care Unit admission criteria for haemato-oncological patients: a basis for clinical guidelines implementation
Recent advances in supportive care and progress in the development and use of chemotherapy have considerably improved the prognosis of many children with malignancy, thus the need for intensive care admission and management is increasing, reaching about 40% of patients throughout the disease course....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PAGEPress Publications
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133495/ https://www.ncbi.nlm.nih.gov/pubmed/21772950 http://dx.doi.org/10.4081/pr.2011.e13 |
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author | Piastra, Marco Fognani, Giuliana Franceschi, Alessia |
author_facet | Piastra, Marco Fognani, Giuliana Franceschi, Alessia |
author_sort | Piastra, Marco |
collection | PubMed |
description | Recent advances in supportive care and progress in the development and use of chemotherapy have considerably improved the prognosis of many children with malignancy, thus the need for intensive care admission and management is increasing, reaching about 40% of patients throughout the disease course. Cancer remains a major death cause in children, though outcomes have considerably improved over the past decades. Prediction of outcome for children with cancer in Pediatric Intensive Care Unit (PICU) obviously requires clinical guidelines, and these are not well defined, as well as admission criteria. Major determinants of negative outcomes remain severe sepsis/septic shock association and respiratory failure, deserving specific approach in children with cancer, particularly those receiving a bone marrow transplantation. A nationwide consensus should be achieved among pediatric intensivists and oncologists regarding the threshold clinical conditions requiring Intensive Care Unit (ICU) admission as well as specific critical care protocols. As demonstrated for the critically ill non-oncologic child, it appears unreasonable that pediatric patients with malignancy can be admitted to an adult Intensive Care Unit ICU. On a national basis a pool of refecence institutions should be identified and early referral to an oncologic PICU is warranted. |
format | Online Article Text |
id | pubmed-3133495 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | PAGEPress Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-31334952011-07-19 Pediatric Intensive Care Unit admission criteria for haemato-oncological patients: a basis for clinical guidelines implementation Piastra, Marco Fognani, Giuliana Franceschi, Alessia Pediatr Rep Case Report Recent advances in supportive care and progress in the development and use of chemotherapy have considerably improved the prognosis of many children with malignancy, thus the need for intensive care admission and management is increasing, reaching about 40% of patients throughout the disease course. Cancer remains a major death cause in children, though outcomes have considerably improved over the past decades. Prediction of outcome for children with cancer in Pediatric Intensive Care Unit (PICU) obviously requires clinical guidelines, and these are not well defined, as well as admission criteria. Major determinants of negative outcomes remain severe sepsis/septic shock association and respiratory failure, deserving specific approach in children with cancer, particularly those receiving a bone marrow transplantation. A nationwide consensus should be achieved among pediatric intensivists and oncologists regarding the threshold clinical conditions requiring Intensive Care Unit (ICU) admission as well as specific critical care protocols. As demonstrated for the critically ill non-oncologic child, it appears unreasonable that pediatric patients with malignancy can be admitted to an adult Intensive Care Unit ICU. On a national basis a pool of refecence institutions should be identified and early referral to an oncologic PICU is warranted. PAGEPress Publications 2011-06-16 /pmc/articles/PMC3133495/ /pubmed/21772950 http://dx.doi.org/10.4081/pr.2011.e13 Text en ©Copyright M. Piastra et al., 2011 This work is licensed under a Creative Commons Attribution 3.0 License (by-nc 3.0). Licensee PAGEPress, Italy |
spellingShingle | Case Report Piastra, Marco Fognani, Giuliana Franceschi, Alessia Pediatric Intensive Care Unit admission criteria for haemato-oncological patients: a basis for clinical guidelines implementation |
title | Pediatric Intensive Care Unit admission criteria for haemato-oncological patients: a basis for clinical guidelines implementation |
title_full | Pediatric Intensive Care Unit admission criteria for haemato-oncological patients: a basis for clinical guidelines implementation |
title_fullStr | Pediatric Intensive Care Unit admission criteria for haemato-oncological patients: a basis for clinical guidelines implementation |
title_full_unstemmed | Pediatric Intensive Care Unit admission criteria for haemato-oncological patients: a basis for clinical guidelines implementation |
title_short | Pediatric Intensive Care Unit admission criteria for haemato-oncological patients: a basis for clinical guidelines implementation |
title_sort | pediatric intensive care unit admission criteria for haemato-oncological patients: a basis for clinical guidelines implementation |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133495/ https://www.ncbi.nlm.nih.gov/pubmed/21772950 http://dx.doi.org/10.4081/pr.2011.e13 |
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