Heterologous expression of pathogen-specific genes ligA and ligB in the saprophyte Leptospira biflexa confers enhanced adhesion to cultured cells and fibronectin

BACKGROUND: In comparison to other bacterial pathogens, our knowledge of the molecular basis of the pathogenesis of leptospirosis is extremely limited. An improved understanding of leptospiral pathogenetic mechanisms requires reliable tools for functional genetic analysis. Leptospiral immunoglobulin...

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Detalles Bibliográficos
Autores principales: Figueira, Cláudio Pereira, Croda, Julio, Choy, Henry A, Haake, David A, Reis, Mitermayer G, Ko, Albert I, Picardeau, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133549/
https://www.ncbi.nlm.nih.gov/pubmed/21658265
http://dx.doi.org/10.1186/1471-2180-11-129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133549/
https://www.ncbi.nlm.nih.gov/pubmed/21658265
http://dx.doi.org/10.1186/1471-2180-11-129

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