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Offspring of Mothers Fed a High Fat Diet Display Hepatic Cell Cycle Inhibition and Associated Changes in Gene Expression and DNA Methylation
The association between an adverse early life environment and increased susceptibility to later-life metabolic disorders such as obesity, type 2 diabetes and cardiovascular disease is described by the developmental origins of health and disease hypothesis. Employing a rat model of maternal high fat...
Autores principales: | Dudley, Kevin J., Sloboda, Deborah M., Connor, Kristin L., Beltrand, Jacques, Vickers, Mark H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133558/ https://www.ncbi.nlm.nih.gov/pubmed/21779332 http://dx.doi.org/10.1371/journal.pone.0021662 |
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