Cargando…
Shaping the synaptic signal: molecular mobility inside and outside the cleft
Rapid communication in the brain relies on the release and diffusion of small transmitter molecules across the synaptic cleft. How these diffuse signals are transformed into cellular responses is determined by the scatter of target postsynaptic receptors, which in turn depends on receptor movement i...
Autores principales: | Rusakov, Dmitri A., Savtchenko, Leonid P., Zheng, Kaiyu, Henley, Jeremy M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Applied Science Publishing
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133640/ https://www.ncbi.nlm.nih.gov/pubmed/21470699 http://dx.doi.org/10.1016/j.tins.2011.03.002 |
Ejemplares similares
-
Nanoscale diffusion in the synaptic cleft and beyond measured with time-resolved fluorescence anisotropy imaging
por: Zheng, Kaiyu, et al.
Publicado: (2017) -
Increased Extrasynaptic Glutamate Escape in Stochastically Shaped Probabilistic Synaptic Environment
por: Savtchenko, Leonid P., et al.
Publicado: (2022) -
Moderate AMPA receptor clustering on the nanoscale can efficiently potentiate synaptic current
por: Savtchenko, Leonid P., et al.
Publicado: (2014) -
Glutamate–Transporter Unbinding in Probabilistic Synaptic Environment Facilitates Activation of Distant NMDA Receptors
por: Savtchenko, Leonid P., et al.
Publicado: (2023) -
Buffering by Transporters Can Spare Geometric Hindrance in Controlling Glutamate Escape
por: Savtchenko, Leonid P., et al.
Publicado: (2021)