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The subcellular localization of the hepatitis C virus non-structural protein NS2 is regulated by an ion channel-independent function of the p7 protein

The hepatitis C virus (HCV) p7 ion channel and non-structural protein 2 (NS2) are both required for efficient assembly and release of nascent virions, yet precisely how these proteins are able to influence this process is unclear. Here, we provide both biochemical and cell biological evidence for a...

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Detalles Bibliográficos
Autores principales: Tedbury, Philip, Welbourn, Sarah, Pause, Arnim, King, Barnabas, Griffin, Stephen, Harris, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133701/
https://www.ncbi.nlm.nih.gov/pubmed/21177929
http://dx.doi.org/10.1099/vir.0.027441-0