Cargando…
Albumin binding ligands and albumin conjugate uptake by cancer cells
The scope of this short review is to summarise the knowledge gleaned from the fate of drugs transported by albumin upon contact with the target cancer cell or cells in inflamed tissues. The authors expertise covers covalently bound drugs and their cellular uptake and release from albumin. This revie...
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133998/ https://www.ncbi.nlm.nih.gov/pubmed/21676260 http://dx.doi.org/10.1186/1758-5996-3-11 |
| _version_ | 1782207942703972352 |
|---|---|
| author | Frei, Eva |
| author_facet | Frei, Eva |
| author_sort | Frei, Eva |
| collection | PubMed |
| description | The scope of this short review is to summarise the knowledge gleaned from the fate of drugs transported by albumin upon contact with the target cancer cell or cells in inflamed tissues. The authors expertise covers covalently bound drugs and their cellular uptake and release from albumin. This review therefore aims to deduce what will happen to drugs such as insulin detemir which is considered to bind non-covalently to albumin and may have a fate similar to fatty acids transported by albumin. |
| format | Online Article Text |
| id | pubmed-3133998 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2011 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-31339982011-07-13 Albumin binding ligands and albumin conjugate uptake by cancer cells Frei, Eva Diabetol Metab Syndr Review The scope of this short review is to summarise the knowledge gleaned from the fate of drugs transported by albumin upon contact with the target cancer cell or cells in inflamed tissues. The authors expertise covers covalently bound drugs and their cellular uptake and release from albumin. This review therefore aims to deduce what will happen to drugs such as insulin detemir which is considered to bind non-covalently to albumin and may have a fate similar to fatty acids transported by albumin. BioMed Central 2011-06-15 /pmc/articles/PMC3133998/ /pubmed/21676260 http://dx.doi.org/10.1186/1758-5996-3-11 Text en Copyright ©2011 Frei; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Review Frei, Eva Albumin binding ligands and albumin conjugate uptake by cancer cells |
| title | Albumin binding ligands and albumin conjugate uptake by cancer cells |
| title_full | Albumin binding ligands and albumin conjugate uptake by cancer cells |
| title_fullStr | Albumin binding ligands and albumin conjugate uptake by cancer cells |
| title_full_unstemmed | Albumin binding ligands and albumin conjugate uptake by cancer cells |
| title_short | Albumin binding ligands and albumin conjugate uptake by cancer cells |
| title_sort | albumin binding ligands and albumin conjugate uptake by cancer cells |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133998/ https://www.ncbi.nlm.nih.gov/pubmed/21676260 http://dx.doi.org/10.1186/1758-5996-3-11 |
| work_keys_str_mv | AT freieva albuminbindingligandsandalbuminconjugateuptakebycancercells |