Tracheoesophageal Fistula Closed by Chemoradiotherapy in Lung Cancer

A 45-year-old man complaining of cough, dyspnea, and difficulty in swallowing was referred to our hospital. Chest CT scan showed a mediastinal mass compressing the trachea. He was diagnosed with poorly differentiated lung carcinoma by percutaneous needle biopsy. Bronchoscopy and upper gastrointestin...

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Autores principales: Honda, Takayuki, Tsuzaki, Yoshihito, Mitaka, Keiko, Fukasawa, Kazuhiro, Miyashita, Yoshihiro, Marino, Kan, Saito, Akitoshi, Oyama, Toshio, Inase, Naohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2011
Materias:
Published Online: July 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134035/
https://www.ncbi.nlm.nih.gov/pubmed/21769294
http://dx.doi.org/10.1159/000330368
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author Honda, Takayuki
Tsuzaki, Yoshihito
Mitaka, Keiko
Fukasawa, Kazuhiro
Miyashita, Yoshihiro
Marino, Kan
Saito, Akitoshi
Oyama, Toshio
Inase, Naohiko
author_facet Honda, Takayuki
Tsuzaki, Yoshihito
Mitaka, Keiko
Fukasawa, Kazuhiro
Miyashita, Yoshihiro
Marino, Kan
Saito, Akitoshi
Oyama, Toshio
Inase, Naohiko
author_sort Honda, Takayuki
collection PubMed
description A 45-year-old man complaining of cough, dyspnea, and difficulty in swallowing was referred to our hospital. Chest CT scan showed a mediastinal mass compressing the trachea. He was diagnosed with poorly differentiated lung carcinoma by percutaneous needle biopsy. Bronchoscopy and upper gastrointestinal endoscopy revealed a tracheoesophageal fistula (TEF). Long-lasting febrile neutropenia made it impossible to continue chemotherapy, but a course of radiotherapy (total 61 Gy) was completed. The next endoscopy revealed closure of the TEF. Chemoradiotherapy (CRT) has been reported to close TEF in esophageal cancer, but the risk of a CRT-induced worsening of the fistula has dissuaded physicians from using CRT to treat TEF in lung cancer patients. CRT may serve as a palliative treatment for TEF in lung cancer as well as esophageal cancer.
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spelling pubmed-31340352011-07-18 Tracheoesophageal Fistula Closed by Chemoradiotherapy in Lung Cancer Honda, Takayuki Tsuzaki, Yoshihito Mitaka, Keiko Fukasawa, Kazuhiro Miyashita, Yoshihiro Marino, Kan Saito, Akitoshi Oyama, Toshio Inase, Naohiko Case Rep Oncol Published Online: July 2011 A 45-year-old man complaining of cough, dyspnea, and difficulty in swallowing was referred to our hospital. Chest CT scan showed a mediastinal mass compressing the trachea. He was diagnosed with poorly differentiated lung carcinoma by percutaneous needle biopsy. Bronchoscopy and upper gastrointestinal endoscopy revealed a tracheoesophageal fistula (TEF). Long-lasting febrile neutropenia made it impossible to continue chemotherapy, but a course of radiotherapy (total 61 Gy) was completed. The next endoscopy revealed closure of the TEF. Chemoradiotherapy (CRT) has been reported to close TEF in esophageal cancer, but the risk of a CRT-induced worsening of the fistula has dissuaded physicians from using CRT to treat TEF in lung cancer patients. CRT may serve as a palliative treatment for TEF in lung cancer as well as esophageal cancer. S. Karger AG 2011-07-09 /pmc/articles/PMC3134035/ /pubmed/21769294 http://dx.doi.org/10.1159/000330368 Text en Copyright © 2011 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published Online: July 2011
Honda, Takayuki
Tsuzaki, Yoshihito
Mitaka, Keiko
Fukasawa, Kazuhiro
Miyashita, Yoshihiro
Marino, Kan
Saito, Akitoshi
Oyama, Toshio
Inase, Naohiko
Tracheoesophageal Fistula Closed by Chemoradiotherapy in Lung Cancer
title Tracheoesophageal Fistula Closed by Chemoradiotherapy in Lung Cancer
title_full Tracheoesophageal Fistula Closed by Chemoradiotherapy in Lung Cancer
title_fullStr Tracheoesophageal Fistula Closed by Chemoradiotherapy in Lung Cancer
title_full_unstemmed Tracheoesophageal Fistula Closed by Chemoradiotherapy in Lung Cancer
title_short Tracheoesophageal Fistula Closed by Chemoradiotherapy in Lung Cancer
title_sort tracheoesophageal fistula closed by chemoradiotherapy in lung cancer
topic Published Online: July 2011
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134035/
https://www.ncbi.nlm.nih.gov/pubmed/21769294
http://dx.doi.org/10.1159/000330368
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