T-helper cells in the etiopathogenesis of periodontal disease: A mini review

Our traditional understanding of the T-helper (Th)1/Th2 paradigm in periodontal disease has undergone considerable changes in recent years. This review focuses on the Th subsets, including the recently identified cells of the CD4 lineage, their activation pathways and effector function in periodonta...

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Detalles Bibliográficos
Autores principales: Arun, K. V., Talwar, Avaneendra, Kumar, T. S. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134046/
https://www.ncbi.nlm.nih.gov/pubmed/21772714
http://dx.doi.org/10.4103/0972-124X.82255
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author Arun, K. V.
Talwar, Avaneendra
Kumar, T. S. S.
author_facet Arun, K. V.
Talwar, Avaneendra
Kumar, T. S. S.
author_sort Arun, K. V.
collection PubMed
description Our traditional understanding of the T-helper (Th)1/Th2 paradigm in periodontal disease has undergone considerable changes in recent years. This review focuses on the Th subsets, including the recently identified cells of the CD4 lineage, their activation pathways and effector function in periodontal disease. The roles of Th17 and regulatory T (Treg) cells in disease pathogenesis have been explored. Newer Th subsets such as Th9 and Th22 cells and their potential role in periodontal disease have also been outlined.
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spelling pubmed-31340462011-07-19 T-helper cells in the etiopathogenesis of periodontal disease: A mini review Arun, K. V. Talwar, Avaneendra Kumar, T. S. S. J Indian Soc Periodontol Review Article Our traditional understanding of the T-helper (Th)1/Th2 paradigm in periodontal disease has undergone considerable changes in recent years. This review focuses on the Th subsets, including the recently identified cells of the CD4 lineage, their activation pathways and effector function in periodontal disease. The roles of Th17 and regulatory T (Treg) cells in disease pathogenesis have been explored. Newer Th subsets such as Th9 and Th22 cells and their potential role in periodontal disease have also been outlined. Medknow Publications 2011 /pmc/articles/PMC3134046/ /pubmed/21772714 http://dx.doi.org/10.4103/0972-124X.82255 Text en © Journal of Indian Society of Periodontology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Arun, K. V.
Talwar, Avaneendra
Kumar, T. S. S.
T-helper cells in the etiopathogenesis of periodontal disease: A mini review
title T-helper cells in the etiopathogenesis of periodontal disease: A mini review
title_full T-helper cells in the etiopathogenesis of periodontal disease: A mini review
title_fullStr T-helper cells in the etiopathogenesis of periodontal disease: A mini review
title_full_unstemmed T-helper cells in the etiopathogenesis of periodontal disease: A mini review
title_short T-helper cells in the etiopathogenesis of periodontal disease: A mini review
title_sort t-helper cells in the etiopathogenesis of periodontal disease: a mini review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134046/
https://www.ncbi.nlm.nih.gov/pubmed/21772714
http://dx.doi.org/10.4103/0972-124X.82255
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