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Inhibitory effect of cranberry juice on the colonization of Streptococci species: An in vitro study

BACKGROUND: Dental biofilm harboring oral bacteria is highly correlated with the progression of dental diseases. The existence of micro organisms as polyspecies in an oral biofilm and dental plaque has profound implications for the etiology of periodontal disease. The adhesion of streptococci to the...

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Autores principales: Sethi, Ragini, Govila, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134047/
https://www.ncbi.nlm.nih.gov/pubmed/21772721
http://dx.doi.org/10.4103/0972-124X.82271
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author Sethi, Ragini
Govila, Vivek
author_facet Sethi, Ragini
Govila, Vivek
author_sort Sethi, Ragini
collection PubMed
description BACKGROUND: Dental biofilm harboring oral bacteria is highly correlated with the progression of dental diseases. The existence of micro organisms as polyspecies in an oral biofilm and dental plaque has profound implications for the etiology of periodontal disease. The adhesion of streptococci to the tooth surface is the first step in the formation of dental plaque. Antiadhesive agents which can disrupt the biofilm formation can be an effective alternative to antibacterial therapy. MATERIALS AND METHODS: A total of 10 patients both male and female between the age group of 20–40 years were included in the study. Plaque samples were taken and subjected to culturing on rabbit's blood agar plate for the growth of streptococci colonies for 24–48 h. The streptococci colonies were identified and was further subjected to subculturing for 24–48 h with disc containing ethyl alcohol+cranberry extract (Group A) and water+cranberry extract (Group B). Both these groups A and B were further divided into subgroups I, II, III, IV, and V according to concentration 1:2, 1:4, 1:40, 1:100 and 1:600 respectively. RESULTS: Zone of inhibition of Group A with subgroup I disc was 2 mm. while with subgroups II, III, IV, V disc was 4mm. Whereas the zone of inhibition seen of Group B was same (2mm) in subgroups I, II, III, IV discs however a significant zone of inhibition (10mm) was observed in subgroup V disc. CONCLUSION: Cranberry juice (active ingredient: Non dialyzable material) inhibits the adhesion and reverses the coaggregation of various oral micro organisms. The present study revealed that cranberry gel in highly concentrated (1:600) form has an inhibitory effect on the colonization of the streptococci species, and thus can be beneficial in the inhibition of dental plaque formation.
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spelling pubmed-31340472011-07-19 Inhibitory effect of cranberry juice on the colonization of Streptococci species: An in vitro study Sethi, Ragini Govila, Vivek J Indian Soc Periodontol Original Article BACKGROUND: Dental biofilm harboring oral bacteria is highly correlated with the progression of dental diseases. The existence of micro organisms as polyspecies in an oral biofilm and dental plaque has profound implications for the etiology of periodontal disease. The adhesion of streptococci to the tooth surface is the first step in the formation of dental plaque. Antiadhesive agents which can disrupt the biofilm formation can be an effective alternative to antibacterial therapy. MATERIALS AND METHODS: A total of 10 patients both male and female between the age group of 20–40 years were included in the study. Plaque samples were taken and subjected to culturing on rabbit's blood agar plate for the growth of streptococci colonies for 24–48 h. The streptococci colonies were identified and was further subjected to subculturing for 24–48 h with disc containing ethyl alcohol+cranberry extract (Group A) and water+cranberry extract (Group B). Both these groups A and B were further divided into subgroups I, II, III, IV, and V according to concentration 1:2, 1:4, 1:40, 1:100 and 1:600 respectively. RESULTS: Zone of inhibition of Group A with subgroup I disc was 2 mm. while with subgroups II, III, IV, V disc was 4mm. Whereas the zone of inhibition seen of Group B was same (2mm) in subgroups I, II, III, IV discs however a significant zone of inhibition (10mm) was observed in subgroup V disc. CONCLUSION: Cranberry juice (active ingredient: Non dialyzable material) inhibits the adhesion and reverses the coaggregation of various oral micro organisms. The present study revealed that cranberry gel in highly concentrated (1:600) form has an inhibitory effect on the colonization of the streptococci species, and thus can be beneficial in the inhibition of dental plaque formation. Medknow Publications 2011 /pmc/articles/PMC3134047/ /pubmed/21772721 http://dx.doi.org/10.4103/0972-124X.82271 Text en © Journal of Indian Society of Periodontology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Sethi, Ragini
Govila, Vivek
Inhibitory effect of cranberry juice on the colonization of Streptococci species: An in vitro study
title Inhibitory effect of cranberry juice on the colonization of Streptococci species: An in vitro study
title_full Inhibitory effect of cranberry juice on the colonization of Streptococci species: An in vitro study
title_fullStr Inhibitory effect of cranberry juice on the colonization of Streptococci species: An in vitro study
title_full_unstemmed Inhibitory effect of cranberry juice on the colonization of Streptococci species: An in vitro study
title_short Inhibitory effect of cranberry juice on the colonization of Streptococci species: An in vitro study
title_sort inhibitory effect of cranberry juice on the colonization of streptococci species: an in vitro study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134047/
https://www.ncbi.nlm.nih.gov/pubmed/21772721
http://dx.doi.org/10.4103/0972-124X.82271
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