Using Rhodamine 123 Accumulation in CD8(+) Cells as a Surrogate Indicator to Study the P-Glycoprotein Modulating Effect of Cepharanthine Hydrochloride In Vivo

The purpose of this study was the use of rhodamine 123 (Rho123) accumulation in peripheral blood CD8(+)cells as a surrogate indicator to evaluate the modulating effect of P-glycoprotein (P-gp) inhibitors in the multidrug resistance (MDR) tumor-bearing mouse model. Rho123 was administered to mice, an...

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Detalles Bibliográficos
Autores principales: Li, Han, Yan, Zhang, Ning, Wang, Xiao-Juan, Guo, Cai-Hong, Zang, Jin-Hua, Jiang, Fang, Ma, Qing-Duan, Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134191/
https://www.ncbi.nlm.nih.gov/pubmed/21765632
http://dx.doi.org/10.1155/2011/281651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134191/
https://www.ncbi.nlm.nih.gov/pubmed/21765632
http://dx.doi.org/10.1155/2011/281651

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