Cargando…

Using Rhodamine 123 Accumulation in CD8(+) Cells as a Surrogate Indicator to Study the P-Glycoprotein Modulating Effect of Cepharanthine Hydrochloride In Vivo

The purpose of this study was the use of rhodamine 123 (Rho123) accumulation in peripheral blood CD8(+)cells as a surrogate indicator to evaluate the modulating effect of P-glycoprotein (P-gp) inhibitors in the multidrug resistance (MDR) tumor-bearing mouse model. Rho123 was administered to mice, an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Han, Yan, Zhang, Ning, Wang, Xiao-Juan, Guo, Cai-Hong, Zang, Jin-Hua, Jiang, Fang, Ma, Qing-Duan, Wang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134191/ https://www.ncbi.nlm.nih.gov/pubmed/21765632 http://dx.doi.org/10.1155/2011/281651

Ejemplares similares

Evaluation of P-Glycoprotein Inhibitory Potential Using a Rhodamine 123 Accumulation Assay
por: Jouan, Elodie, et al.
Publicado: (2016)

In vitro activity of cepharanthine hydrochloride against clinical wild-type and lamivudine-resistant hepatitis B virus isolates
por: Zhou, Yu-Bing, et al.
Publicado: (2012)

Cepharanthine Hydrochloride Improves Cisplatin Chemotherapy and Enhances Immunity by Regulating Intestinal Microbes in Mice
por: Zhou, Pengjun, et al.
Publicado: (2019)

Cepharanthine hydrochloride inhibits the Wnt/β-catenin/Hedgehog signaling axis in liver cancer
por: Su, Gui-Feng, et al.
Publicado: (2022)

Downregulation of MDR1 Gene by Cepharanthine Hydrochloride Is Related to the Activation of c-Jun/JNK in K562/ADR Cells
por: Han, Li, et al.
Publicado: (2014)

Cepharanthine hydrochloride reverses the mdr1 (P-glycoprotein)-mediated esophageal squamous cell carcinoma cell cisplatin resistance through JNK and p53 signals
por: Zhou, Pengjun, et al.
Publicado: (2017)

Effects of berberine on pharmacokinetics of midazolam and rhodamine 123 in rats in vivo
por: Xin, Hua-Wen, et al.
Publicado: (2016)

Correction: Cepharanthine hydrochloride reverses the mdr1 (P-glycoprotein)-mediated esophageal squamous cell carcinoma cell cisplatin resistance through JNK and p53 signals
por: Zhou, Pengjun, et al.
Publicado: (2021)

Pharmacological Activity of Cepharanthine
por: Liu, Ke, et al.
Publicado: (2023)

Active transport of rhodamine 123 by the human multidrug transporter P‐glycoprotein involves two independent outer gates
por: Nasim, Fauzia, et al.
Publicado: (2020)

Is Rhodamine 123 an Appropriate Fluorescent Probe to Assess P-Glycoprotein Mediated Multidrug Resistance in Vinblastine-Resistant CHO Cells?
por: Pétriz, Jordi, et al.
Publicado: (1997)

Cepharanthine in Experimental Tuberculosis
por: Sirsi, M., et al.
Publicado: (1952)

In vitro antiplasmodial activity of cepharanthine
por: Desgrouas, Camille, et al.
Publicado: (2014)

In vitro and in vivo combination of cepharanthine with anti-malarial drugs
por: Desgrouas, Camille, et al.
Publicado: (2014)

Acceleration of MRP-associated efflux of rhodamine 123 by genistein and related compounds.
por: Versantvoort, C. H., et al.
Publicado: (1996)

Retracted: Downregulation of MDR1 Gene by Cepharanthine Hydrochloride Is Related to the Activation of c-Jun/JNK in K562/ADR Cells
por: International, BioMed Research
Publicado: (2016)

Comparison of staurosporine and four analogues: their effects on growth, rhodamine 123 retention and binding to P-glycoprotein in multidrug-resistant MCF-7/Adr cells.
por: Budworth, J., et al.
Publicado: (1996)

Pharmacological Effects and Clinical Prospects of Cepharanthine
por: Liang, Di, et al.
Publicado: (2022)

Transfer of rhodamine-123 into the brain and cerebrospinal fluid of fetal, neonatal and adult rats
por: Koehn, Liam M., et al.
Publicado: (2021)

Characterization of Rhodamine-123 as a Tracer Dye for Use In In vitro Drug Transport Assays
por: Forster, Samantha, et al.
Publicado: (2012)

Determination of Polyhexamethylene Biguanide Hydrochloride Using a Lactone-Rhodamine B-Based Fluorescence Optode
por: Funaki, Akane, et al.
Publicado: (2020)

Rhodamine123 reveals heterogeneity within murine Lin-, Sca-1+ hemopoietic stem cells
Publicado: (1992)

Differentiation of promyelocytic (HL-60) cells into mature granulocytes: mitochondrial-specific rhodamine 123 fluorescence
Publicado: (1983)

Cepharanthine Dry Powder Inhaler for the Treatment of Acute Lung Injury
por: Liang, Di, et al.
Publicado: (2023)

Cepharanthine inhibits dengue virus production and cytokine secretion
por: Phumesin, Patta, et al.
Publicado: (2022)

Effects of Hydrothermal Time on Structure and Photocatalytic Property of Titanium Dioxide for Degradation of Rhodamine B and Tetracycline Hydrochloride
por: Tang, Mao, et al.
Publicado: (2021)

Magnetic Luffa-Leaf-Derived Hierarchical Porous Biochar for Efficient Removal of Rhodamine B and Tetracycline Hydrochloride
por: Su, Yingjie, et al.
Publicado: (2022)

Is the Mitochondrial Membrane Potential (∆Ψ) Correctly Assessed? Intracellular and Intramitochondrial Modifications of the ∆Ψ Probe, Rhodamine 123
por: Zorova, Ljubava D., et al.
Publicado: (2022)

Toxicological Impact and in Vivo Tracing of Rhodamine Functionalised ZIF-8 Nanoparticles
por: Goyal, Prateek, et al.
Publicado: (2022)

Cepharanthine and Curcumin inhibited mitochondrial apoptosis induced by PCV2
por: Xu, Yinlan, et al.
Publicado: (2020)

Network analysis-based strategy to investigate the protective effect of cepharanthine on rat acute respiratory distress syndrome
por: Chen, Chen, et al.
Publicado: (2022)

The Mechanism of CD8(+) T Cells for Reducing Myofibroblasts Accumulation during Renal Fibrosis
por: Gao, Min, et al.
Publicado: (2021)

Status of mitochondria in living human fibroblasts during growth and senescence in vitro: use of the laser dye rhodamine 123
Publicado: (1981)

Cannabidiol (CBD) Inhibited Rhodamine-123 Efflux in Cultured Vascular Endothelial Cells and Astrocytes Under Hypoxic Conditions
por: Auzmendi, Jerónimo, et al.
Publicado: (2020)

Microphysiological Conditions Do Not Affect MDR1-Mediated Transport of Rhodamine 123 above an Artificial Proximal Tubule
por: Namazian Jam, Negin, et al.
Publicado: (2023)

In vitro inhibitory effects of cepharanthine on human liver cytochrome P450 enzymes
por: Zhang, Xunge, et al.
Publicado: (2020)

Repurposing of berbamine hydrochloride to inhibit Ebola virus by targeting viral glycoprotein
por: Yi, Dongrong, et al.
Publicado: (2022)

Cepharanthine: An update of its mode of action, pharmacological properties and medical applications
por: Bailly, Christian
Publicado: (2019)

Preparation and Evaluation of Self-emulsifying Drug Delivery System (SEDDS) of Cepharanthine
por: Yang, Xinggang, et al.
Publicado: (2021)

Cepharanthine loaded nanoparticles coated with macrophage membranes for lung inflammation therapy
por: Lu, Caihong, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_g4mq1ph61ktpk1kkrjmo71i777