Computational Perspectives into Plasmepsins Structure—Function Relationship: Implications to Inhibitors Design

The development of efficient and selective antimalariais remains a challenge for the pharmaceutical industry. The aspartic proteases plasmepsins, whose inhibition leads to parasite death, are classified as targets for the design of potent drugs. Combinatorial synthesis is currently being used to gen...

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Detalles Bibliográficos
Autores principales: Gil L., Alejandro, Valiente, Pedro A., Pascutti, Pedro G., Pons, Tirso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134243/
https://www.ncbi.nlm.nih.gov/pubmed/21760810
http://dx.doi.org/10.1155/2011/657483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134243/
https://www.ncbi.nlm.nih.gov/pubmed/21760810
http://dx.doi.org/10.1155/2011/657483

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