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Computational Perspectives into Plasmepsins Structure—Function Relationship: Implications to Inhibitors Design
The development of efficient and selective antimalariais remains a challenge for the pharmaceutical industry. The aspartic proteases plasmepsins, whose inhibition leads to parasite death, are classified as targets for the design of potent drugs. Combinatorial synthesis is currently being used to gen...
Autores principales: | Gil L., Alejandro, Valiente, Pedro A., Pascutti, Pedro G., Pons, Tirso |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134243/ https://www.ncbi.nlm.nih.gov/pubmed/21760810 http://dx.doi.org/10.1155/2011/657483 |
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