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Hypothyroidism and Thyroid Substitution: Historical Aspects
The last part of the 19th century was a period of great achievements in medicine and endocrinology. The thyroid gland evolved from being considered a rudimentary structure to an organ related to specific diseases. The singular importance of iodine became acknowledged. Graves-Basedow's disease w...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE-Hindawi Access to Research
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134382/ https://www.ncbi.nlm.nih.gov/pubmed/21760981 http://dx.doi.org/10.4061/2011/809341 |
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author | Lindholm, J. Laurberg, P. |
author_facet | Lindholm, J. Laurberg, P. |
author_sort | Lindholm, J. |
collection | PubMed |
description | The last part of the 19th century was a period of great achievements in medicine and endocrinology. The thyroid gland evolved from being considered a rudimentary structure to an organ related to specific diseases. The singular importance of iodine became acknowledged. Graves-Basedow's disease was described. Surgical treatment evolved with extraordinary speed. Theodor Kocher observed that the clinical picture in patients after total thyroidectomy was similar to the one seen in cretinism. In 1850, the first case of hypothyroidism or myxedema was described. Less than 50 years later, effective treatment was introduced. Another 50 years later, autoimmune thyroiditis was ascertained as the most frequent cause of hypothyroidism (in areas with no iodine deficiency). This paper gives a short survey of the history of hypothyroidism and its treatment. |
format | Online Article Text |
id | pubmed-3134382 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | SAGE-Hindawi Access to Research |
record_format | MEDLINE/PubMed |
spelling | pubmed-31343822011-07-14 Hypothyroidism and Thyroid Substitution: Historical Aspects Lindholm, J. Laurberg, P. J Thyroid Res Review Article The last part of the 19th century was a period of great achievements in medicine and endocrinology. The thyroid gland evolved from being considered a rudimentary structure to an organ related to specific diseases. The singular importance of iodine became acknowledged. Graves-Basedow's disease was described. Surgical treatment evolved with extraordinary speed. Theodor Kocher observed that the clinical picture in patients after total thyroidectomy was similar to the one seen in cretinism. In 1850, the first case of hypothyroidism or myxedema was described. Less than 50 years later, effective treatment was introduced. Another 50 years later, autoimmune thyroiditis was ascertained as the most frequent cause of hypothyroidism (in areas with no iodine deficiency). This paper gives a short survey of the history of hypothyroidism and its treatment. SAGE-Hindawi Access to Research 2011-06-08 /pmc/articles/PMC3134382/ /pubmed/21760981 http://dx.doi.org/10.4061/2011/809341 Text en Copyright © 2011 J. Lindholm and P. Laurberg. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Lindholm, J. Laurberg, P. Hypothyroidism and Thyroid Substitution: Historical Aspects |
title | Hypothyroidism and Thyroid Substitution: Historical Aspects |
title_full | Hypothyroidism and Thyroid Substitution: Historical Aspects |
title_fullStr | Hypothyroidism and Thyroid Substitution: Historical Aspects |
title_full_unstemmed | Hypothyroidism and Thyroid Substitution: Historical Aspects |
title_short | Hypothyroidism and Thyroid Substitution: Historical Aspects |
title_sort | hypothyroidism and thyroid substitution: historical aspects |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134382/ https://www.ncbi.nlm.nih.gov/pubmed/21760981 http://dx.doi.org/10.4061/2011/809341 |
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