Expression of phosphorylated raf kinase inhibitor protein (pRKIP) is a predictor of lung cancer survival

BACKGROUND: Raf-1 kinase inhibitor protein (RKIP) has been reported to negatively regulate signal kinases of major survival pathways. RKIP activity is modulated in part by phosphorylation on Serine 153 by protein kinase C, which leads to dissociation of RKIP from Raf-1. RKIP expression is low in man...

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Detalles Bibliográficos
Autores principales: Huerta-Yepez, Sara, Yoon, Nam K, Hernandez-Cueto, Angeles, Mah, Vei, Rivera-Pazos, Clara M, Chatterjee, Devasis, Vega, Mario I, Maresh, Erin L, Horvath, Steve, Chia, David, Bonavida, Benjamin, Goodglick, Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134426/
https://www.ncbi.nlm.nih.gov/pubmed/21689459
http://dx.doi.org/10.1186/1471-2407-11-259

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