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Defining the Specificity of Cotranslationally Acting Chaperones by Systematic Analysis of mRNAs Associated with Ribosome-Nascent Chain Complexes

Polypeptides exiting the ribosome must fold and assemble in the crowded environment of the cell. Chaperones and other protein homeostasis factors interact with newly translated polypeptides to facilitate their folding and correct localization. Despite the extensive efforts, little is known about the...

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Detalles Bibliográficos
Autores principales: del Alamo, Marta, Hogan, Daniel J., Pechmann, Sebastian, Albanese, Veronique, Brown, Patrick O., Frydman, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134442/
https://www.ncbi.nlm.nih.gov/pubmed/21765803
http://dx.doi.org/10.1371/journal.pbio.1001100