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Gastrodin Inhibits Expression of Inducible NO Synthase, Cyclooxygenase-2 and Proinflammatory Cytokines in Cultured LPS-Stimulated Microglia via MAPK Pathways
BACKGROUND: Microglial activation plays an important role in neurodegenerative diseases by producing several proinflammatory enzymes and proinflammatory cytokines. The phenolic glucoside gastrodin, a main constituent of a Chinese herbal medicine, has been known to display anti-inflammatory propertie...
Autores principales: | Dai, Ji-Nan, Zong, Yi, Zhong, Lian-Mei, Li, Yue-Min, Zhang, Wei, Bian, Li-Gong, Ai, Qing-Long, Liu, Yi-Dan, Sun, Jun, Lu, Di |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134470/ https://www.ncbi.nlm.nih.gov/pubmed/21765922 http://dx.doi.org/10.1371/journal.pone.0021891 |
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