A dual acting compound releasing nitric oxide (NO) and ibuprofen, NCX 320, shows significant therapeutic effects in a mouse model of muscular dystrophy

A resolutive therapy for muscular dystrophies, a heterogeneous group of genetic diseases leading to muscular degeneration and in the severe forms to death, is still lacking. Since inflammation and defects in nitric oxide generation are recognized key pathogenic events in muscular dystrophy, we have...

Descripción completa

Detalles Bibliográficos
Autores principales: Sciorati, Clara, Miglietta, Daniela, Buono, Roberta, Pisa, Viviana, Cattaneo, Dario, Azzoni, Emanuele, Brunelli, Silvia, Clementi, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134707/
https://www.ncbi.nlm.nih.gov/pubmed/21609764
http://dx.doi.org/10.1016/j.phrs.2011.05.003

Ejemplares similares

Ejemplares similares