Development and Implementation of a High Throughput Screen for the Human Sperm-Specific Isoform of Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDHS)

Glycolytic isozymes that are restricted to the male germline are potential targets for the development of reversible, non-hormonal male contraceptives. GAPDHS, the sperm-specific isoform of glyceraldehyde-3-phosphate dehydrogenase, is an essential enzyme for glycolysis making it an attractive target...

Descripción completa

Detalles Bibliográficos
Autores principales: Sexton, Jonathan Z, Danshina, Polina V, Lamson, David R, Hughes, Mark, House, Alan J, Yeh, Li-An, O’Brien, Deborah A, Williams, Kevin P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134944/
https://www.ncbi.nlm.nih.gov/pubmed/21760877
http://dx.doi.org/10.2174/1875397301105010030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134944/
https://www.ncbi.nlm.nih.gov/pubmed/21760877
http://dx.doi.org/10.2174/1875397301105010030

Ejemplares similares