Pharmacokinetic Considerations for Digoxin in Older People

OBJECTIVE: This review aims to arm readers with a deep understanding of pharmacokinetics of digoxin. DATA SOURCES: Pharmacology and pharmacokinetic references texts, and peer reviewed medical journal manuscripts indexed on Medline included based on currency, accuracy and appropriateness. RESULTS: ch...

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Detalles Bibliográficos
Autores principales: Currie, Geoffrey M, Wheat, Janelle M, Kiat, Hosen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134946/
https://www.ncbi.nlm.nih.gov/pubmed/21769303
http://dx.doi.org/10.2174/1874192401105010130
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author Currie, Geoffrey M
Wheat, Janelle M
Kiat, Hosen
author_facet Currie, Geoffrey M
Wheat, Janelle M
Kiat, Hosen
author_sort Currie, Geoffrey M
collection PubMed
description OBJECTIVE: This review aims to arm readers with a deep understanding of pharmacokinetics of digoxin. DATA SOURCES: Pharmacology and pharmacokinetic references texts, and peer reviewed medical journal manuscripts indexed on Medline included based on currency, accuracy and appropriateness. RESULTS: changes to absorption, distribution, metabolism and excretion, increased susceptibility to drug sensitivity, co-existing pathology, polypharmacy. CONCLUSION: A thorough understanding of digoxin pharmacokinetics in the older person is essential for improved therapeutic outcomes, improved compliance, reduced morbidity and improved quality of life.
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spelling pubmed-31349462011-07-18 Pharmacokinetic Considerations for Digoxin in Older People Currie, Geoffrey M Wheat, Janelle M Kiat, Hosen Open Cardiovasc Med J Article OBJECTIVE: This review aims to arm readers with a deep understanding of pharmacokinetics of digoxin. DATA SOURCES: Pharmacology and pharmacokinetic references texts, and peer reviewed medical journal manuscripts indexed on Medline included based on currency, accuracy and appropriateness. RESULTS: changes to absorption, distribution, metabolism and excretion, increased susceptibility to drug sensitivity, co-existing pathology, polypharmacy. CONCLUSION: A thorough understanding of digoxin pharmacokinetics in the older person is essential for improved therapeutic outcomes, improved compliance, reduced morbidity and improved quality of life. Bentham Open 2011-06-15 /pmc/articles/PMC3134946/ /pubmed/21769303 http://dx.doi.org/10.2174/1874192401105010130 Text en © Currie et al.; Licensee Bentham Open. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Article
Currie, Geoffrey M
Wheat, Janelle M
Kiat, Hosen
Pharmacokinetic Considerations for Digoxin in Older People
title Pharmacokinetic Considerations for Digoxin in Older People
title_full Pharmacokinetic Considerations for Digoxin in Older People
title_fullStr Pharmacokinetic Considerations for Digoxin in Older People
title_full_unstemmed Pharmacokinetic Considerations for Digoxin in Older People
title_short Pharmacokinetic Considerations for Digoxin in Older People
title_sort pharmacokinetic considerations for digoxin in older people
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134946/
https://www.ncbi.nlm.nih.gov/pubmed/21769303
http://dx.doi.org/10.2174/1874192401105010130
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