Cargando…
Molecular decoding using luminescence from an entangled porous framework
Chemosensors detect a single target molecule from among several molecules, but cannot differentiate targets from one another. In this study, we report a molecular decoding strategy in which a single host domain accommodates a class of molecules and distinguishes between them with a corresponding rea...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134948/ https://www.ncbi.nlm.nih.gov/pubmed/21266971 http://dx.doi.org/10.1038/ncomms1170 |
_version_ | 1782208035723149312 |
---|---|
author | Takashima, Yohei Martínez, Virginia Martínez Furukawa, Shuhei Kondo, Mio Shimomura, Satoru Uehara, Hiromitsu Nakahama, Masashi Sugimoto, Kunihisa Kitagawa, Susumu |
author_facet | Takashima, Yohei Martínez, Virginia Martínez Furukawa, Shuhei Kondo, Mio Shimomura, Satoru Uehara, Hiromitsu Nakahama, Masashi Sugimoto, Kunihisa Kitagawa, Susumu |
author_sort | Takashima, Yohei |
collection | PubMed |
description | Chemosensors detect a single target molecule from among several molecules, but cannot differentiate targets from one another. In this study, we report a molecular decoding strategy in which a single host domain accommodates a class of molecules and distinguishes between them with a corresponding readout. We synthesized the decoding host by embedding naphthalenediimide into the scaffold of an entangled porous framework that exhibited structural dynamics due to the dislocation of two chemically non-interconnected frameworks. An intense turn-on emission was observed on incorporation of a class of aromatic compounds, and the resulting luminescent colour was dependent on the chemical substituent of the aromatic guest. This unprecedented chemoresponsive, multicolour luminescence originates from an enhanced naphthalenediimide–aromatic guest interaction because of the induced-fit structural transformation of the entangled framework. We demonstrate that the cooperative structural transition in mesoscopic crystal domains results in a nonlinear sensor response to the guest concentration. |
format | Online Article Text |
id | pubmed-3134948 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-31349482011-07-13 Molecular decoding using luminescence from an entangled porous framework Takashima, Yohei Martínez, Virginia Martínez Furukawa, Shuhei Kondo, Mio Shimomura, Satoru Uehara, Hiromitsu Nakahama, Masashi Sugimoto, Kunihisa Kitagawa, Susumu Nat Commun Article Chemosensors detect a single target molecule from among several molecules, but cannot differentiate targets from one another. In this study, we report a molecular decoding strategy in which a single host domain accommodates a class of molecules and distinguishes between them with a corresponding readout. We synthesized the decoding host by embedding naphthalenediimide into the scaffold of an entangled porous framework that exhibited structural dynamics due to the dislocation of two chemically non-interconnected frameworks. An intense turn-on emission was observed on incorporation of a class of aromatic compounds, and the resulting luminescent colour was dependent on the chemical substituent of the aromatic guest. This unprecedented chemoresponsive, multicolour luminescence originates from an enhanced naphthalenediimide–aromatic guest interaction because of the induced-fit structural transformation of the entangled framework. We demonstrate that the cooperative structural transition in mesoscopic crystal domains results in a nonlinear sensor response to the guest concentration. Nature Publishing Group 2011-01 2011-01-25 /pmc/articles/PMC3134948/ /pubmed/21266971 http://dx.doi.org/10.1038/ncomms1170 Text en Copyright © 2011, Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved. http://creativecommons.org/licenses/by-nc-sa/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/ |
spellingShingle | Article Takashima, Yohei Martínez, Virginia Martínez Furukawa, Shuhei Kondo, Mio Shimomura, Satoru Uehara, Hiromitsu Nakahama, Masashi Sugimoto, Kunihisa Kitagawa, Susumu Molecular decoding using luminescence from an entangled porous framework |
title | Molecular decoding using luminescence from an entangled porous framework |
title_full | Molecular decoding using luminescence from an entangled porous framework |
title_fullStr | Molecular decoding using luminescence from an entangled porous framework |
title_full_unstemmed | Molecular decoding using luminescence from an entangled porous framework |
title_short | Molecular decoding using luminescence from an entangled porous framework |
title_sort | molecular decoding using luminescence from an entangled porous framework |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134948/ https://www.ncbi.nlm.nih.gov/pubmed/21266971 http://dx.doi.org/10.1038/ncomms1170 |
work_keys_str_mv | AT takashimayohei moleculardecodingusingluminescencefromanentangledporousframework AT martinezvirginiamartinez moleculardecodingusingluminescencefromanentangledporousframework AT furukawashuhei moleculardecodingusingluminescencefromanentangledporousframework AT kondomio moleculardecodingusingluminescencefromanentangledporousframework AT shimomurasatoru moleculardecodingusingluminescencefromanentangledporousframework AT ueharahiromitsu moleculardecodingusingluminescencefromanentangledporousframework AT nakahamamasashi moleculardecodingusingluminescencefromanentangledporousframework AT sugimotokunihisa moleculardecodingusingluminescencefromanentangledporousframework AT kitagawasusumu moleculardecodingusingluminescencefromanentangledporousframework |