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Homoallylic amines by reductive inter- and intramolecular coupling of allenes and nitriles
The one-pot hydrozirconation of allenes and nitriles followed by an in situ transmetalation of the allylzirconocene with dimethylzinc or zinc chloride provides functionalized homoallylic amines. An intramolecular version of this process leads to 3-aminotetrahydrofurans and 3-aminotetrahydropyrans.
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135093/ https://www.ncbi.nlm.nih.gov/pubmed/21804878 http://dx.doi.org/10.3762/bjoc.7.94 |
| _version_ | 1782208057402458112 |
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| author | Wipf, Peter Manojlovic, Marija D |
| author_facet | Wipf, Peter Manojlovic, Marija D |
| author_sort | Wipf, Peter |
| collection | PubMed |
| description | The one-pot hydrozirconation of allenes and nitriles followed by an in situ transmetalation of the allylzirconocene with dimethylzinc or zinc chloride provides functionalized homoallylic amines. An intramolecular version of this process leads to 3-aminotetrahydrofurans and 3-aminotetrahydropyrans. |
| format | Online Article Text |
| id | pubmed-3135093 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2011 |
| publisher | Beilstein-Institut |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-31350932011-07-29 Homoallylic amines by reductive inter- and intramolecular coupling of allenes and nitriles Wipf, Peter Manojlovic, Marija D Beilstein J Org Chem Full Research Paper The one-pot hydrozirconation of allenes and nitriles followed by an in situ transmetalation of the allylzirconocene with dimethylzinc or zinc chloride provides functionalized homoallylic amines. An intramolecular version of this process leads to 3-aminotetrahydrofurans and 3-aminotetrahydropyrans. Beilstein-Institut 2011-06-17 /pmc/articles/PMC3135093/ /pubmed/21804878 http://dx.doi.org/10.3762/bjoc.7.94 Text en Copyright © 2011, Wipf and Manojlovic https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
| spellingShingle | Full Research Paper Wipf, Peter Manojlovic, Marija D Homoallylic amines by reductive inter- and intramolecular coupling of allenes and nitriles |
| title | Homoallylic amines by reductive inter- and intramolecular coupling of allenes and nitriles |
| title_full | Homoallylic amines by reductive inter- and intramolecular coupling of allenes and nitriles |
| title_fullStr | Homoallylic amines by reductive inter- and intramolecular coupling of allenes and nitriles |
| title_full_unstemmed | Homoallylic amines by reductive inter- and intramolecular coupling of allenes and nitriles |
| title_short | Homoallylic amines by reductive inter- and intramolecular coupling of allenes and nitriles |
| title_sort | homoallylic amines by reductive inter- and intramolecular coupling of allenes and nitriles |
| topic | Full Research Paper |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135093/ https://www.ncbi.nlm.nih.gov/pubmed/21804878 http://dx.doi.org/10.3762/bjoc.7.94 |
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