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Comparison of FRAX Scores of Southern California Females of Mexican Descent Using US Hispanic and Mexico Database

Introduction. Regional differences for fracture risk of US Hispanics may vary by national origin. In California, where a majority of the Hispanic population is of Mexican descent, it is of interest to compare the FRAX absolute risk using the US Hispanic and Mexico databases. Methods. We collected FR...

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Autores principales: Nasser, Keaton M., Focil, Augusto, Silverman, Stuart L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135157/
https://www.ncbi.nlm.nih.gov/pubmed/21772973
http://dx.doi.org/10.4061/2011/531359
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author Nasser, Keaton M.
Focil, Augusto
Silverman, Stuart L.
author_facet Nasser, Keaton M.
Focil, Augusto
Silverman, Stuart L.
author_sort Nasser, Keaton M.
collection PubMed
description Introduction. Regional differences for fracture risk of US Hispanics may vary by national origin. In California, where a majority of the Hispanic population is of Mexican descent, it is of interest to compare the FRAX absolute risk using the US Hispanic and Mexico databases. Methods. We collected FRAX risk factor data from 134 women of Mexican descent in southern California. The FRAX risk score was calculated using the US Hispanic and Mexican databases, using the NOF guidelines for osteoporosis to compare the number of patients that would be selected for treatment. Results. The 10-year absolute risk of major osteoporotic fracture among women of Mexican descent using the US Hispanic database was 4.82 ± 5.03 (95% CI 3.97–5.67) compared to 4.86 ± 4.72 (CI 3.98–5.44) using the Mexico database (P = .94). The 10-year risk for hip fracture was 0.86 ± 1.78 (CI .56–1.16) compared to 1.12 ± 1.97 (CI .79–1.45, P = .26). The mean conformity for meeting the interventional threshold by either risk score was 94.8%. Conclusion. The comparison between the FRAX databases demonstrates a similarity in the absolute risk of major osteoporotic fracture. Differences are noted in the absolute number of hip fracture subjects at risk, but there is a high rate of conformity.
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spelling pubmed-31351572011-07-19 Comparison of FRAX Scores of Southern California Females of Mexican Descent Using US Hispanic and Mexico Database Nasser, Keaton M. Focil, Augusto Silverman, Stuart L. J Osteoporos Research Article Introduction. Regional differences for fracture risk of US Hispanics may vary by national origin. In California, where a majority of the Hispanic population is of Mexican descent, it is of interest to compare the FRAX absolute risk using the US Hispanic and Mexico databases. Methods. We collected FRAX risk factor data from 134 women of Mexican descent in southern California. The FRAX risk score was calculated using the US Hispanic and Mexican databases, using the NOF guidelines for osteoporosis to compare the number of patients that would be selected for treatment. Results. The 10-year absolute risk of major osteoporotic fracture among women of Mexican descent using the US Hispanic database was 4.82 ± 5.03 (95% CI 3.97–5.67) compared to 4.86 ± 4.72 (CI 3.98–5.44) using the Mexico database (P = .94). The 10-year risk for hip fracture was 0.86 ± 1.78 (CI .56–1.16) compared to 1.12 ± 1.97 (CI .79–1.45, P = .26). The mean conformity for meeting the interventional threshold by either risk score was 94.8%. Conclusion. The comparison between the FRAX databases demonstrates a similarity in the absolute risk of major osteoporotic fracture. Differences are noted in the absolute number of hip fracture subjects at risk, but there is a high rate of conformity. SAGE-Hindawi Access to Research 2011-05-25 /pmc/articles/PMC3135157/ /pubmed/21772973 http://dx.doi.org/10.4061/2011/531359 Text en Copyright © 2011 Keaton M. Nasser et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Nasser, Keaton M.
Focil, Augusto
Silverman, Stuart L.
Comparison of FRAX Scores of Southern California Females of Mexican Descent Using US Hispanic and Mexico Database
title Comparison of FRAX Scores of Southern California Females of Mexican Descent Using US Hispanic and Mexico Database
title_full Comparison of FRAX Scores of Southern California Females of Mexican Descent Using US Hispanic and Mexico Database
title_fullStr Comparison of FRAX Scores of Southern California Females of Mexican Descent Using US Hispanic and Mexico Database
title_full_unstemmed Comparison of FRAX Scores of Southern California Females of Mexican Descent Using US Hispanic and Mexico Database
title_short Comparison of FRAX Scores of Southern California Females of Mexican Descent Using US Hispanic and Mexico Database
title_sort comparison of frax scores of southern california females of mexican descent using us hispanic and mexico database
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135157/
https://www.ncbi.nlm.nih.gov/pubmed/21772973
http://dx.doi.org/10.4061/2011/531359
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