Continuous flow hydrogenation using polysilane-supported palladium/alumina hybrid catalysts

Continuous flow systems for hydrogenation using polysilane-supported palladium/alumina (Pd/(PSi–Al(2)O(3))) hybrid catalysts were developed. Our original Pd/(PSi–Al(2)O(3)) catalysts were used successfully in these systems and the hydrogenation of unsaturated C–C bonds and a nitro group, deprotectio...

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Autores principales: Oyamada, Hidekazu, Naito, Takeshi, Kobayashi, Shū
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2011
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135162/
https://www.ncbi.nlm.nih.gov/pubmed/21804868
http://dx.doi.org/10.3762/bjoc.7.83
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author Oyamada, Hidekazu
Naito, Takeshi
Kobayashi, Shū
author_facet Oyamada, Hidekazu
Naito, Takeshi
Kobayashi, Shū
author_sort Oyamada, Hidekazu
collection PubMed
description Continuous flow systems for hydrogenation using polysilane-supported palladium/alumina (Pd/(PSi–Al(2)O(3))) hybrid catalysts were developed. Our original Pd/(PSi–Al(2)O(3)) catalysts were used successfully in these systems and the hydrogenation of unsaturated C–C bonds and a nitro group, deprotection of a carbobenzyloxy (Cbz) group, and a dehalogenation reaction proceeded smoothly. The catalyst retained high activity for at least 8 h under neat conditions.
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spelling pubmed-31351622011-07-29 Continuous flow hydrogenation using polysilane-supported palladium/alumina hybrid catalysts Oyamada, Hidekazu Naito, Takeshi Kobayashi, Shū Beilstein J Org Chem Letter Continuous flow systems for hydrogenation using polysilane-supported palladium/alumina (Pd/(PSi–Al(2)O(3))) hybrid catalysts were developed. Our original Pd/(PSi–Al(2)O(3)) catalysts were used successfully in these systems and the hydrogenation of unsaturated C–C bonds and a nitro group, deprotection of a carbobenzyloxy (Cbz) group, and a dehalogenation reaction proceeded smoothly. The catalyst retained high activity for at least 8 h under neat conditions. Beilstein-Institut 2011-05-31 /pmc/articles/PMC3135162/ /pubmed/21804868 http://dx.doi.org/10.3762/bjoc.7.83 Text en Copyright © 2011, Oyamada et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Letter
Oyamada, Hidekazu
Naito, Takeshi
Kobayashi, Shū
Continuous flow hydrogenation using polysilane-supported palladium/alumina hybrid catalysts
title Continuous flow hydrogenation using polysilane-supported palladium/alumina hybrid catalysts
title_full Continuous flow hydrogenation using polysilane-supported palladium/alumina hybrid catalysts
title_fullStr Continuous flow hydrogenation using polysilane-supported palladium/alumina hybrid catalysts
title_full_unstemmed Continuous flow hydrogenation using polysilane-supported palladium/alumina hybrid catalysts
title_short Continuous flow hydrogenation using polysilane-supported palladium/alumina hybrid catalysts
title_sort continuous flow hydrogenation using polysilane-supported palladium/alumina hybrid catalysts
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135162/
https://www.ncbi.nlm.nih.gov/pubmed/21804868
http://dx.doi.org/10.3762/bjoc.7.83
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