Individual Rac GTPases Mediate Aspects of Prostate Cancer Cell and Bone Marrow Endothelial Cell Interactions

The Rho GTPases organize the actin cytoskeleton and are involved in cancer metastasis. Previously, we demonstrated that RhoC GTPase was required for PC-3 prostate cancer cell invasion. Targeted down-regulation of RhoC led to sustained activation of Rac1 GTPase and morphological, molecular and phenot...

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Detalles Bibliográficos
Autores principales: Chatterjee, Moumita, Sequeira, Linda, Jenkins-Kabaila, Mashariki, Dubyk, Cara W., Pathak, Surabhi, van Golen, Kenneth L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135208/
https://www.ncbi.nlm.nih.gov/pubmed/21776386
http://dx.doi.org/10.1155/2011/541851

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