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Na(+),K(+)-pump stimulation improves contractility in isolated muscles of mice with hyperkalemic periodic paralysis
In patients with hyperkalemic periodic paralysis (HyperKPP), attacks of muscle weakness or paralysis are triggered by K(+) ingestion or rest after exercise. Force can be restored by muscle work or treatment with β(2)-adrenoceptor agonists. A missense substitution corresponding to a mutation in the s...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135321/ https://www.ncbi.nlm.nih.gov/pubmed/21708955 http://dx.doi.org/10.1085/jgp.201010586 |