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B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells
T follicular helper cells (Tfh cells) localize to follicles where they provide growth and selection signals to mutated germinal center (GC) B cells, thus promoting their differentiation into high affinity long-lived plasma cells and memory B cells. T-dependent B cell differentiation also occurs extr...
Autores principales: | Lee, Sau K., Rigby, Robert J., Zotos, Dimitra, Tsai, Louis M., Kawamoto, Shimpei, Marshall, Jennifer L., Ramiscal, Roybel R., Chan, Tyani D., Gatto, Dominique, Brink, Robert, Yu, Di, Fagarasan, Sidonia, Tarlinton, David M., Cunningham, Adam F., Vinuesa, Carola G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135363/ https://www.ncbi.nlm.nih.gov/pubmed/21708925 http://dx.doi.org/10.1084/jem.20102065 |
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