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B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells

T follicular helper cells (Tfh cells) localize to follicles where they provide growth and selection signals to mutated germinal center (GC) B cells, thus promoting their differentiation into high affinity long-lived plasma cells and memory B cells. T-dependent B cell differentiation also occurs extr...

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Detalles Bibliográficos
Autores principales: Lee, Sau K., Rigby, Robert J., Zotos, Dimitra, Tsai, Louis M., Kawamoto, Shimpei, Marshall, Jennifer L., Ramiscal, Roybel R., Chan, Tyani D., Gatto, Dominique, Brink, Robert, Yu, Di, Fagarasan, Sidonia, Tarlinton, David M., Cunningham, Adam F., Vinuesa, Carola G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135363/
https://www.ncbi.nlm.nih.gov/pubmed/21708925
http://dx.doi.org/10.1084/jem.20102065

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