Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance in Toxoplasma gondii

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Apicomplexa are important pathogens that include the causative agents of malaria, toxoplasmosis, and cryptosporidiosis. Apicomplexan parasites contain a relict chloroplast, the apicoplast. The apicoplast is indispensable and an attractive drug target. The apicoplast is home to a 1-deoxy-d-xylulose-5...

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Detalles Bibliográficos
Autores principales: Nair, Sethu C., Brooks, Carrie F., Goodman, Christopher D., Strurm, Angelika, McFadden, Geoffrey I., Sundriyal, Sandeep, Anglin, Justin L., Song, Yongcheng, Moreno, Silvia N.J., Striepen, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135366/
https://www.ncbi.nlm.nih.gov/pubmed/21690250
http://dx.doi.org/10.1084/jem.20110039
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