Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation

The pathogenesis of chronic lymphocytic leukemia (CLL), the most common leukemia in adults, is still largely unknown. The full spectrum of genetic lesions that are present in the CLL genome, and therefore the number and identity of dysregulated cellular pathways, have not been identified. By combini...

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Detalles Bibliográficos
Autores principales: Fabbri, Giulia, Rasi, Silvia, Rossi, Davide, Trifonov, Vladimir, Khiabanian, Hossein, Ma, Jing, Grunn, Adina, Fangazio, Marco, Capello, Daniela, Monti, Sara, Cresta, Stefania, Gargiulo, Ernesto, Forconi, Francesco, Guarini, Anna, Arcaini, Luca, Paulli, Marco, Laurenti, Luca, Larocca, Luigi M., Marasca, Roberto, Gattei, Valter, Oscier, David, Bertoni, Francesco, Mullighan, Charles G., Foá, Robin, Pasqualucci, Laura, Rabadan, Raul, Dalla-Favera, Riccardo, Gaidano, Gianluca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135373/
https://www.ncbi.nlm.nih.gov/pubmed/21670202
http://dx.doi.org/10.1084/jem.20110921

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