Common variants in TMPRSS6 are associated with iron status and erythrocyte volume

We report a genome-wide association study to iron status. We identify an association of SNPs in TPMRSS6 to serum iron (rs855791, combined P = 1.5×10(−20)), transferrin saturation (combined P = 2.2×10(−23)), and erythrocyte mean cell volume (MCV, combined P = 1.1×10(−10)). We also find suggestive evi...

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Detalles Bibliográficos
Autores principales: Benyamin, Beben, Ferreira, Manuel A. R., Willemsen, Gonneke, Gordon, Scott, Middelberg, Rita P. S., McEvoy, Brian P., Hottenga, Jouke-Jan, Henders, Anjali K., Campbell, Megan J., Wallace, Leanne, Frazer, Ian H., Heath, Andrew C., de Geus, Eco J. C., Nyholt, Dale R., Visscher, Peter M., Penninx, Brenda W., Boomsma, Dorret I., Martin, Nicholas G., Montgomery, Grant W., Whitfield, John B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135421/
https://www.ncbi.nlm.nih.gov/pubmed/19820699
http://dx.doi.org/10.1038/ng.456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135421/
https://www.ncbi.nlm.nih.gov/pubmed/19820699
http://dx.doi.org/10.1038/ng.456

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