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Down-regulation of epithelial cadherin is required to initiate metastatic outgrowth of breast cancer

Reduced epithelial cadherin (E-cad) is a hallmark of invasive carcinomas that have acquired epithelial-mesenchymal transition (EMT) phenotypes. Here we show that down-regulated E-cad expression induced by transforming growth factor-β (TGF-β) and EMT preceded breast cancer outgrowth in three-dimensio...

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Detalles Bibliográficos
Autores principales:	Wendt, Michael K., Taylor, Molly A., Schiemann, Barbara J., Schiemann, William P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135469/ https://www.ncbi.nlm.nih.gov/pubmed/21613543 http://dx.doi.org/10.1091/mbc.E11-04-0306

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