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Reduced Mad2 expression keeps relaxed kinetochores from arresting budding yeast in mitosis
Chromosome segregation depends on the spindle checkpoint, which delays anaphase until all chromosomes have bound microtubules and have been placed under tension. The Mad1–Mad2 complex is an essential component of the checkpoint. We studied the consequences of removing one copy of MAD2 in diploid cel...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135471/ https://www.ncbi.nlm.nih.gov/pubmed/21593209 http://dx.doi.org/10.1091/mbc.E09-01-0029 |