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Histopathologic characterization of the BTBR mouse model of autistic-like behavior reveals selective changes in neurodevelopmental proteins and adult hippocampal neurogenesis

BACKGROUND: The inbred mouse strain BTBR T+ tf/J (BTBR) exhibits behavioral deficits that mimic the core deficits of autism. Neuroanatomically, the BTBR strain is also characterized by a complete absence of the corpus callosum. The goal of this study was to identify novel molecular and cellular chan...

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Detalles Bibliográficos
Autores principales: Stephenson, Diane T, O'Neill, Sharon M, Narayan, Sapna, Tiwari, Aadhya, Arnold, Elizabeth, Samaroo, Harry D, Du, Fu, Ring, Robert H, Campbell, Brian, Pletcher, Mathew, Vaidya, Vidita A, Morton, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135520/
https://www.ncbi.nlm.nih.gov/pubmed/21575186
http://dx.doi.org/10.1186/2040-2392-2-7