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Unsuccessful therapy with adefovir and entecavir-tenofovir in a patient with chronic hepatitis B infection with previous resistance to lamivudine: a fourteen-year evolution of hepatitis B virus mutations

BACKGROUND: Complex mutants can be selected under sequential selective pressure by HBV therapy. To determine hepatitis B virus genomic evolution during antiviral therapy we characterized the HBV quasi-species in a patient who did no respond to therapy following lamivudine breakthrough for a period o...

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Detalles Bibliográficos
Autores principales: Cassino, Lucila, Benetti, Silvina, Fay, Fabian, Tanno, Hugo, Quarleri, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135534/
https://www.ncbi.nlm.nih.gov/pubmed/21696601
http://dx.doi.org/10.1186/1471-2334-11-178