Immunogenicity in mice and rhesus monkeys vaccinated with recombinant vaccinia virus expressing bivalent E7E6 fusion proteins from human papillomavirus types 16 and 18

BACKGROUND: Persistent infection with high-risk human papillomavirus (HPV) is a predominant cause of cervical cancer, and HPV16 and HPV18 occur in 50% and 20% of cervical cancer cases, respectively. The viral oncogenes E6 and E7 are constitutively expressed by HPV-associated tumour cells and can the...

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Detalles Bibliográficos
Autores principales: Zhao, Li, Liu, Binlei, Ren, Jiao, Feng, Jing, Pang, Zheng, Gao, Jian, Zhang, Hui, Tan, Wenjie, Tian, Houwen, Ruan, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135557/
https://www.ncbi.nlm.nih.gov/pubmed/21672263
http://dx.doi.org/10.1186/1743-422X-8-302

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