Out-of-Frame T Cell Receptor Beta Transcripts Are Eliminated by Multiple Pathways In Vivo

Non-productive antigen receptor genes with frame shifts generated during the assembly of these genes are found in many mature lymphocytes. Transcripts from these genes have premature termination codons (PTCs) and could encode truncated proteins if they are not either inactivated or destroyed by nons...

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Detalles Bibliográficos
Autores principales: Mahowald, Grace K., Mahowald, Michael A., Moon, Clara, Khor, Bernard, Sleckman, Barry P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135592/
https://www.ncbi.nlm.nih.gov/pubmed/21765899
http://dx.doi.org/10.1371/journal.pone.0021627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135592/
https://www.ncbi.nlm.nih.gov/pubmed/21765899
http://dx.doi.org/10.1371/journal.pone.0021627

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