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Out-of-Frame T Cell Receptor Beta Transcripts Are Eliminated by Multiple Pathways In Vivo
Non-productive antigen receptor genes with frame shifts generated during the assembly of these genes are found in many mature lymphocytes. Transcripts from these genes have premature termination codons (PTCs) and could encode truncated proteins if they are not either inactivated or destroyed by nons...
Autores principales: | Mahowald, Grace K., Mahowald, Michael A., Moon, Clara, Khor, Bernard, Sleckman, Barry P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135592/ https://www.ncbi.nlm.nih.gov/pubmed/21765899 http://dx.doi.org/10.1371/journal.pone.0021627 |
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