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Galectin-3C Inhibits Tumor Growth and Increases the Anticancer Activity of Bortezomib in a Murine Model of Human Multiple Myeloma
Galectin-3 is a human lectin involved in many cellular processes including differentiation, apoptosis, angiogenesis, neoplastic transformation, and metastasis. We evaluated galectin-3C, an N-terminally truncated form of galectin-3 that is thought to act as a dominant negative inhibitor, as a potenti...
Autores principales: | Mirandola, Leonardo, Yu, Yuefei, Chui, Kitty, Jenkins, Marjorie R., Cobos, Everardo, John, Constance M., Chiriva-Internati, Maurizio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135605/ https://www.ncbi.nlm.nih.gov/pubmed/21765917 http://dx.doi.org/10.1371/journal.pone.0021811 |
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