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The Putative RNA Helicase HELZ Promotes Cell Proliferation, Translation Initiation and Ribosomal Protein S6 Phosphorylation

The hypoxia–inducible transcription factor (HIF) is a key component of the cellular adaptation mechanisms to hypoxic conditions. HIFα subunits are degraded by prolyl-4-hydroxylase domain (PHD) enzyme-dependent prolyl-4-hydroxylation of LxxLAP motifs that confer oxygen-dependent proteolytic degradati...

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Detalles Bibliográficos
Autores principales:	Hasgall, Philippe A., Hoogewijs, David, Faza, Marius B., Panse, Vikram G., Wenger, Roland H., Camenisch, Gieri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135610/ https://www.ncbi.nlm.nih.gov/pubmed/21765940 http://dx.doi.org/10.1371/journal.pone.0022107

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