Simulated Microgravity Compromises Mouse Oocyte Maturation by Disrupting Meiotic Spindle Organization and Inducing Cytoplasmic Blebbing

In the present study, we discovered that mouse oocyte maturation was inhibited by simulated microgravity via disturbing spindle organization. We cultured mouse oocytes under microgravity condition simulated by NASA's rotary cell culture system, examined the maturation rate and observed the spin...

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Detalles Bibliográficos
Autores principales: Wu, Changli, Guo, Xinzheng, Wang, Fang, Li, Xiaoshuang, Tian, X. Cindy, Li, Li, Wu, Zhenfang, Zhang, Shouquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135614/
https://www.ncbi.nlm.nih.gov/pubmed/21765954
http://dx.doi.org/10.1371/journal.pone.0022214

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