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Heparin Induces Harmless Fibril Formation in Amyloidogenic W7FW14F Apomyoglobin and Amyloid Aggregation in Wild-Type Protein In Vitro
Glycosaminoglycans (GAGs) are frequently associated with amyloid deposits in most amyloid diseases, and there is evidence to support their active role in amyloid fibril formation. The purpose of this study was to obtain structural insight into GAG-protein interactions and to better elucidate the mol...
Autores principales: | Vilasi, Silvia, Sarcina, Rosalba, Maritato, Rosa, De Simone, Antonella, Irace, Gaetano, Sirangelo, Ivana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135624/ https://www.ncbi.nlm.nih.gov/pubmed/21779376 http://dx.doi.org/10.1371/journal.pone.0022076 |
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